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Is 7-days home BP measurement comparable to 24-hours Ambulatory BP Measurement?
medRxiv - Cardiovascular Medicine Pub Date : 2021-10-12 , DOI: 10.1101/2021.10.11.21264844
Sheikh Mohammed Shariful Islam , Chandan Karmakar , Syed Imran Ahmed , Ralph Maddison

High blood pressure (BP) or hypertension is a significant risk factor for the global burden of cardiovascular diseases. Home blood pressure measurements (HBPM) have been recommended for hypertension diagnosis, treatment initiation and medication titration, but guidelines for the number of measurements and duration are inconsistent. This study compared the accuracy of 3 home BP measurements per day for seven days with 24-hour ambulatory BP measurements. We examined 24-hour ambulatory BP measurements (ABPM) and HBPM during-morning, afternoon, and evening each day for seven days in healthy community living volunteers. Standardized Bland-Altman scatterplots and limits of agreement (LOA) were used to assess absolute reliability and the variability of measurement biases. We used nonparametric Mann-Whitney U-tests to compare the mean (SD) of the devices. Correlations between HBPM and 24-hour ABPM measurements were statistically significant at p<0.05. The high correlation coefficient (r=0.75) was observed between the systolic BP retrieved from two devices compared to moderate correlation (r=0.46) among diastolic BP. A significant difference was found for systolic BP (P<0.05) between the HBPM and ABPM but was non-significant for diastolic BP (P>0.05). In Bland-Altman plots, the LOA between HBPM and ABPM was 0.07-26.23 mmHg for SBP and 11.24 -16.20 mmHg for DBP. The overall mean difference (bias) in SBP and DBP was 13.08 and 2.48, respectively. Our results suggest that HBPM three times per day for seven days can potentially be used where ABPM is unavailable. Further studies in a diverse group of people with hypertension are needed.

中文翻译:

7 天的家庭血压测量与 24 小时动态血压测量是否具有可比性?

高血压 (BP) 或高血压是全球心血管疾病负担的重要危险因素。家庭血压测量 (HBPM) 已被推荐用于高血压诊断、治疗开始和药物滴定,但测量次数和持续时间的指南不一致。本研究比较了 7 天内每天 3 次家庭血压测量与 24 小时动态血压测量的准确性。我们检查了健康社区生活志愿者的 7 天每天早上、下午和晚上的 24 小时动态血压测量值 (ABPM) 和 HBPM。标准化的 Bland-Altman 散点图和一致限 (LOA) 用于评估绝对可靠性和测量偏差的可变性。我们使用非参数 Mann-Whitney U 检验来比较设备的均值 (SD)。HBPM 和 24 小时 ABPM 测量值之间的相关性在 p<0.05 处具有统计学显着性。与舒张压之间的中等相关性 (r=0.46) 相比,从两个设备获取的收缩压之间观察到高相关系数 (r=0.75)。HBPM 和 ABPM 之间的收缩压存在显着差异(P<0.05),但舒张压不显着(P>0.05)。在 Bland-Altman 图中,HBPM 和 ABPM 之间的 LOA 对于 SBP 为 0.07-26.23 mmHg,对于 DBP 为 11.24 -16.20 mmHg。SBP 和 DBP 的总体平均差异(偏差)分别为 13.08 和 2.48。我们的结果表明,在 ABPM 不可用的情况下,可以使用 HBPM 每天 3 次,持续 7 天。需要对不同的高血压人群进行进一步研究。
更新日期:2021-10-14
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