Dysfunctional efferocytosis impairs clearance of apoptotic cells in disease. A new study shows that glutamine catabolism supports efficient apoptotic cell efferocytosis via non-canonical glutamine transamination but not canonical GLUD1-dependent α-ketoglutarate production, in a process that may operate in human atherosclerosis.

中文翻译：

---

efferocytes 的谷氨酰胺暴饮暴食

功能失调的细胞增多症会损害疾病中凋亡细胞的清除。一项新的研究表明，谷氨酰胺分解代谢通过非经典的谷氨酰胺转氨作用支持有效的凋亡细胞胞吐作用，但不支持经典的 GLUD1 依赖性 α-酮戊二酸产生，这一过程可能在人类动脉粥样硬化中起作用。