The fasting-mimicking diet is a five-day cycle of near total fasting each month that extends healthspan in male mice. In this issue of Nature Metabolism, Mishra et al. demonstrate life-extending and cardioprotective benefits of the fasting-mimicking diet in middle-aged female mice that are consuming a high-fat diet.

中文翻译：

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定期禁食可防止女性脂肪减少

禁食模拟饮食是一个为期五天的循环，每个月几乎完全禁食，从而延长了雄性小鼠的健康寿命。在本期《自然代谢》中，Mishra 等人。在食用高脂肪饮食的中年雌性小鼠中展示模拟禁食饮食对延长寿命和心脏保护的益处。