ABSTRACT

Purpose

To investigate retinal and optic disc microvascular alterations using optical coherence tomography angiography (OCTA) in women with polycystic ovary syndrome (PCOS).

Methods

Forty-six eyes of 23 patients with PCOS (PCOS group), and 50 eyes of 25 sex and age-matched healthy controls (control group) were included in this cross-sectional study. Foveal retinal thickness, peripapillary retinal nerve fiber layer (RNFL) thickness, vessel density in different sections of the retina and optic disc were analyzed by OCTA.

Results

The superficial parafoveal vessel densities were significantly lower in PCOS group compared to the control group (53.7 ± 4.0%, and 55.4 ± 2.7%, respectively, p = .02). The deep retinal vessel densities, foveal retinal thicknesses and RNFL thicknesses, whole image of optic disc radial peripapillary capillary densities, foveal avascular zone and flow areas were similar between the groups (p > .05 for all).

Conclusion

OCTA analysis indicates that patients with PCOS tend to have lower superficial parafoveal vessel densities.

中文翻译：

---

多囊卵巢综合征视网膜和视盘微血管形成的调查：光学相干断层扫描血管造影研究

摘要

目的

使用光学相干断层扫描血管造影术 (OCTA) 研究多囊卵巢综合征 (PCOS) 女性的视网膜和视盘微血管改变。

方法

本横断面研究纳入了 23 名 PCOS 患者的 46 只眼（PCOS 组）和 25 名性别和年龄匹配的健康对照者的 50 只眼（对照组）。通过OCTA分析了中心凹视网膜厚度、视盘周围视网膜神经纤维层（RNFL）厚度、视网膜和视盘不同切片的血管密度。

结果

与对照组相比，PCOS 组的浅表中心凹旁血管密度显着降低（分别为 53.7 ± 4.0% 和 55.4 ± 2.7%，p = .02）。深部视网膜血管密度、中央凹视网膜厚度和 RNFL 厚度、视神经盘径向周围毛细血管密度、中央凹无血管区和流动区域的整体图像在各组之间相似（所有p > .05）。

结论

OCTA 分析表明，PCOS 患者的浅表中心凹旁血管密度往往较低。