ABSTRACT

Purpose

To compare Indocyanine Green (ICGA) and fundus fluorescein angiography (FFA) with Optical Coherence Tomography Angiography (OCTA) findings in toxoplasmic chorioretinitis (TCR).

Methods

Patients affected by active TCR were included. FFA, ICGA, and OCTA images were analyzed and lesions were compared between different modalities. Satellite dark dots (SDD) were compared between modalities.

Results

Fifteen patients were enrolled. The mean lesion area was similar between fundus photography (FP), FFA, and OCTA-Retina. The mean lesion area was similar between ICGA and OCTA-Choroid slab. ICGA and OCTA-Choroid showed a larger extension of the lesion compared to FP, FFA, and OCTA-Retina (p = .01, 0.0001, and 0.0002 for ICG angiography and p = .03, 0.008, and 0.0002 for OCTA-Choroid, respectively). On OCTA B-scans, the retinal flow defects were smaller than the underlying choroidal non-perfusion. The number of SDD was similar between ICGA and OCTA.

Conclusions

OCTA is a reliable method to assess retinal and choroidal involvement in TCR. OCTA confirmed a wider involvement of the choroid than the retina.

中文翻译：

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急性眼后部弓形虫病：光学相干断层扫描血管造影和染料血管造影研究

摘要

目的

比较吲哚菁绿 (ICGA) 和眼底荧光血管造影 (FFA) 与光学相干断层造影血管造影 (OCTA) 在弓形体脉络膜视网膜炎 (TCR) 中的发现。

方法

受活动性 TCR 影响的患者也包括在内。分析了 FFA、ICGA 和 OCTA 图像，并比较了不同模式之间的病变。卫星暗点 (SDD) 在模态之间进行了比较。

结果

招募了 15 名患者。眼底摄影 (FP)、FFA 和 OCTA-Retina 的平均病变面积相似。ICGA 和 OCTA-脉络膜板的平均病变面积相似。与 FP、FFA 和 OCTA-Retina 相比，ICGA 和 OCTA-Choroid 显示出更大的病变扩展（ICG 血管造影的p = .01、0.0001 和 0.0002，OCTA-Choroid 的p = .03、0.008 和 0.0002，分别）。在 OCTA B 扫描中，视网膜血流缺陷小于潜在的脉络膜非灌注。ICGA 和 OCTA 的 SDD 数量相似。

结论

OCTA 是评估 TCR 中视网膜和脉络膜受累的可靠方法。OCTA 证实脉络膜比视网膜更广泛地受累。