High-flow nasal cannula is widely used in acute hypoxemic respiratory failure due to coronavirus disease 2019, yet data regarding its effectiveness is lacking. More evidence is needed to guide patient selection, timing of high-flow nasal cannula initiation, and resource allocation. We aimed to assess time to discharge and time to death in severe coronavirus disease 2019 in patients treated with high-flow nasal cannula compared with matched controls. We also evaluated the ability of the respiratory rate-oxygenation ratio to predict progression to invasive mechanical ventilation.

中文翻译：

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高流量鼻插管在 2019 年冠状病毒肺炎中的有效性：一项回顾性队列研究。

高流量鼻插管广泛用于 2019 冠状病毒病引起的急性低氧性呼吸衰竭，但缺乏有关其有效性的数据。需要更多的证据来指导患者的选择、高流量鼻插管启动的时机和资源分配。我们的目的是评估与匹配的对照组相比，接受高流量鼻插管治疗的严重冠状病毒病 2019 患者的出院时间和死亡时间。我们还评估了呼吸率-氧合比预测有创机械通气进展的能力。