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The Influence of Hypercapnia and Atmospheric Pressure on the PaO2/FIO2 Ratio-Pathophysiologic Considerations, a Case Series, and Introduction of a Clinical Tool.
Critical Care Medicine ( IF 7.7 ) Pub Date : 2021-10-12 , DOI: 10.1097/ccm.0000000000005316
Vincent J H S Gilissen 1 , Mark V Koning 1 , Markus Klimek 2
Affiliation  

The ratio between PaO2 and FIO2 is used as a marker for impaired oxygenation and acute respiratory distress syndrome classification. However, any discrepancy between FIO2 and O2 fraction in the alveolus affects the PaO2/FIO2 ratio. Correcting the PaO2/FIO2 ratios using the alveolar gas equation may result in an improved reflection of the pulmonary situation. This study investigates the difference between standard and corrected PaO2/FIO2 in magnitude, its correlation with the mortality of acute respiratory distress syndrome classification, and trends over time.

中文翻译:

高碳酸血症和大气压力对 PaO2/FIO2 比率的影响——病理生理学考虑、病例系列和临床工具介绍。

PaO2 和 FIO2 之间的比率用作氧合受损和急性呼吸窘迫综合征分类的标志。然而,肺泡中 FIO2 和 O2 分数之间的任何差异都会影响 PaO2/FIO2 比率。使用肺泡气体方程校正 PaO2/FIO2 比率可能会改善肺状况的反映。本研究调查了标准 PaO2/FIO2 与校正后 PaO2/FIO2 在量级上的差异、其与急性呼吸窘迫综合征分类死亡率的相关性以及随时间变化的趋势。
更新日期:2021-10-12
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