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A Practical Guide to Analyzing and Reporting the Movement of Nanoscale Swimmers
ACS Nano ( IF 17.1 ) Pub Date : 2021-10-12 , DOI: 10.1021/acsnano.1c07503
Wei Wang 1 , Thomas E Mallouk 2
Affiliation  

The recent invention of nanoswimmers—synthetic, powered objects with characteristic lengths in the range of 10–500 nm—has sparked widespread interest among scientists and the general public. As more researchers from different backgrounds enter the field, the study of nanoswimmers offers new opportunities but also significant experimental and theoretical challenges. In particular, the accurate characterization of nanoswimmers is often hindered by strong Brownian motion, convective effects, and the lack of a clear way to visualize them. When coupled with improper experimental designs and imprecise practices in data analysis, these issues can translate to results and conclusions that are inconsistent and poorly reproducible. This Perspective follows the course of a typical nanoswimmer investigation from synthesis through to applications and offers suggestions for best practices in reporting experimental details, recording videos, plotting trajectories, calculating and analyzing mobility, eliminating drift, and performing control experiments, in order to improve the reliability of the reported results.

中文翻译:

分析和报告纳米级游泳者运动的实用指南

最近发明的纳米游泳者——特征长度在 10-500 纳米范围内的合成动力物体——引起了科学家和公众的广泛兴趣。随着越来越多来自不同背景的研究人员进入该领域,纳米游泳者的研究提供了新的机会,但也带来了重大的实验和理论挑战。特别是,纳米游泳者的准确表征常常受到强烈布朗运动、对流效应以及缺乏清晰的可视化方法的阻碍。当加上不正确的实验设计和数据分析中的不精确实践时,这些问题可能会转化为不一致且重现性差的结果和结论。
更新日期:2021-10-26
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