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MOXIDECTIN AND IVERMECTIN INHIBIT SARS-COV-2 REPLICATION IN VERO E6 CELLS BUT NOT IN HUMAN PRIMARY AIRWAY EPITHELIUM CELLS
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-10-11 , DOI: 10.1128/aac.01543-21 Nilima Dinesh Kumar 1, 2 , Bram M Ter Ellen 2 , Ellen M Bouma 2 , Berit Troost 2 , Denise P I van de Pol 2 , Heidi H van der Ende-Metselaar 2 , Djoke van Gosliga 3 , Leonie Apperloo 4 , Orestes A Carpaij 5 , Maarten van den Berge 5 , Martijn C Nawijn 4 , Ymkje Stienstra 6 , Izabela A Rodenhuis-Zybert 2 , Jolanda M Smit 2
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-10-11 , DOI: 10.1128/aac.01543-21 Nilima Dinesh Kumar 1, 2 , Bram M Ter Ellen 2 , Ellen M Bouma 2 , Berit Troost 2 , Denise P I van de Pol 2 , Heidi H van der Ende-Metselaar 2 , Djoke van Gosliga 3 , Leonie Apperloo 4 , Orestes A Carpaij 5 , Maarten van den Berge 5 , Martijn C Nawijn 4 , Ymkje Stienstra 6 , Izabela A Rodenhuis-Zybert 2 , Jolanda M Smit 2
Affiliation
Antiviral therapies are urgently needed to treat and limit the development of severe
COVID-19 disease. Ivermectin, a broad-spectrum anti-parasitic agent, has been shown
to have anti-SARS-CoV-2 activity in Vero cells at a concentration of 5 μM. These ...
中文翻译：
莫西菌素和伊维菌素抑制 VERO E6 细胞中的 SARS-COV-2 复制，但不抑制人初级气道上皮细胞中的复制
迫切需要抗病毒疗法来治疗和限制严重的 COVID-19 疾病的发展。伊维菌素是一种广谱抗寄生虫药，已被证明在浓度为 5 μM 的 Vero 细胞中具有抗 SARS-CoV-2 活性。这些 ...
更新日期：2021-10-12
中文翻译：
莫西菌素和伊维菌素抑制 VERO E6 细胞中的 SARS-COV-2 复制，但不抑制人初级气道上皮细胞中的复制
迫切需要抗病毒疗法来治疗和限制严重的 COVID-19 疾病的发展。伊维菌素是一种广谱抗寄生虫药，已被证明在浓度为 5 μM 的 Vero 细胞中具有抗 SARS-CoV-2 活性。这些 ...
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