DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated Candidiasis,Antimicrobial Agents and Chemotherapy

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DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated Candidiasis
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-10-11 , DOI: 10.1128/aac.01467-21
Suresh Ambati ₁ , Tuyetnhu Pham ₂ , Zachary A Lewis ₂ , Xiaorong Lin ₂ , Richard B Meagher ₁

Affiliation

Candida albicans causes life-threatening disseminated candidiasis. Individuals at greatest risk have weakened immune systems. An outer cell wall, exopolysaccharide matrix, and biofilm rich in oligoglucans and oligomannans help Candida spp. evade host ...

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