RNA-sequencing elucidates drug-specific mechanisms of antibiotic tolerance and resistance in M. abscessus,Antimicrobial Agents and Chemotherapy

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RNA-sequencing elucidates drug-specific mechanisms of antibiotic tolerance and resistance in M. abscessus
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-10-11 , DOI: 10.1128/aac.01509-21
Jodie A Schildkraut ₁ , Jordy P M Coolen ₁ , Sophie Burbaud ₂ , Jasper J N Sangen ₂ , Michael P Kwint ₃ , R Andres Floto ₂ , Huub J M Op den Camp ₄ , Lindsey H M Te Brake ₅ , Heiman F L Wertheim ₁ , Kornelia Neveling ₃ , Wouter Hoefsloot ₆ , Jakko van Ingen ₁

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Mycobacterium abscessus is an opportunistic pathogen notorious for its resistance to most classes of antibiotics and low cure rates. M. abscessus carries an array of mostly unexplored defence mechanisms. A deeper understanding of antibiotic resistance and ...

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