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Repair of sports cartilage injury with tissue engineering scaffold material
Ferroelectrics ( IF 0.6 ) Pub Date : 2021-10-11 , DOI: 10.1080/00150193.2021.1906121
Yueheng Zhang 1
Affiliation  

Abstract

The development of tissue engineering technology provides a new way for cartilage regeneration and repair, and the selection and application of scaffold materials are very important in the repair process. The purpose of this study is to explore the effect of tissue engineering scaffold materials in repairing sports cartilage injury. The purpose of this study is to explore the purpose of this article by experimental analysis, data comparison and other methods combined with the experimental analysis of cartilage repair with tissue engineering scaffold materials. The results showed that the microhardness values of the four kinds of scaffolds were HV536, HV526, HV558 and HV535, which matched with the human bone tissue, and could meet the mechanical property requirements of the implant materials. The microhardness values of the four kinds of scaffolds were in 72 h When the concentration of Ca2+ and Zn2+ released from M3 and M4 scaffolds reached the nucleation threshold of Ca5 (P04)3 (OH) crystal, Ca5 (P04)3 (OH) crystal was formed by combining with PO43-, which made the new bone tissue and scaffolds surface fuze rapidly, thus effectively promoting the repair of bone tissue. It can be concluded that tissue engineering scaffolds are very effective in repairing sports cartilage injury, and zinc containing scaffolds are more excellent. It has laid a foundation for the rapid development and integration of tissue engineering, bioengineering technology and nanotechnology. The new composite technology, which is combined with a variety of materials and technologies, will further meet the needs of both doctors and patients.



中文翻译:

组织工程支架材料修复运动软骨损伤

摘要

组织工程技术的发展为软骨再生和修复提供了新的途径,支架材料的选择和应用在修复过程中非常重要。本研究的目的是探讨组织工程支架材料在修复运动软骨损伤中的作用。本研究的目的是通过实验分析、数据比较等方法,结合组织工程支架材料软骨修复的实验分析,探讨本文的研究目的。结果表明,四种支架的显微硬度值分别为HV536、HV526、HV558和HV535,与人体骨组织相匹配,能够满足植入材料的力学性能要求。M3 和 M4 支架释放的2+和 Zn 2+达到 Ca 5 (P04)3 (OH) 晶体的成核阈值,与 PO 43-结合形成 Ca5 (P04)3 (OH) 晶体,这使得新的骨组织和支架表面迅速引信,从而有效促进骨组织的修复。可以得出结论,组织工程支架修复运动软骨损伤非常有效,含锌支架效果更佳。为组织工程、生物工程技术和纳米技术的快速发展和融合奠定了基础。结合多种材料和技术的新型复合技术将进一步满足医生和患者的需求。

更新日期:2021-10-12
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