Hispanics are disproportionately affected by NAFLD, liver fibrosis, cirrhosis, and HCC. Preventive strategies and noninvasive means to identify those in this population at high risk for liver fibrosis, are urgently needed. We aimed to characterize the gut microbiome signatures and related biological functions associated with liver fibrosis in Hispanics and identify environmental and genetic factors affecting them.

中文翻译：

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西班牙裔人群的肠道微生物组特征与肝纤维化相关，西班牙裔人群是脂肪肝疾病的高危人群


西班牙裔人受 NAFLD、肝纤维化、肝硬化和 HCC 的影响尤为严重。迫切需要预防策略和非侵入性手段来识别肝纤维化高危人群。我们的目的是描述西班牙裔人的肠道微生物特征和与肝纤维化相关的生物功能，并确定影响它们的环境和遗传因素。