ABSTRACT

Background and Objectives

The majority of patients suffering from anxiety disorders in low- and middle-income countries do not receive evidence-based treatments. The Unified Protocol (UP) for the Transdiagnostic Treatment of Emotional Disorders is an evidence-based cognitive–behavioral intervention designed to treat the range of emotional disorders.

Design and Methods

Using a single-case experimental design five patients with panic disorder were assigned to a 3-week baselines assessment phase followed by eight sessions of UP treatment and 4-week follow-up phases. Multiple outcome measures of panic severity, anxiety sensitivity, affectivity, and overall anxiety severity and impairment were administered weekly during the baseline, intervention, and follow-up phases.

Results

At post treatment, all participants showed significant reductions in outcome measures, with changes functionally related to treatment and most improvements maintained at 4-week follow-up.

Conclusion

Findings provide preliminary cross-cultural support for UP and add to the growing body of literature showing UP can be useful for patients with anxiety disorders in low- and middle-income countries with non-Western cultures.

中文翻译：

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恐慌症患者情绪障碍跨诊断治疗统一方案的初步审查：伊朗的单例实验设计

摘要

背景和目标

在低收入和中等收入国家，大多数患有焦虑症的患者没有接受循证治疗。情绪障碍跨诊断治疗的统一方案 (UP) 是一种基于证据的认知行为干预，旨在治疗各种情绪障碍。

设计与方法

使用单病例实验设计，五名恐慌症患者被分配到一个为期 3 周的基线评估阶段，然后是八个疗程的 UP 治疗和 4 周的随访阶段。在基线、干预和后续阶段每周进行恐慌严重程度、焦虑敏感性、情感以及总体焦虑严重程度和损伤的多项结果测量。

结果

在治疗后，所有参与者的结果指标都显着降低，功能上的变化与治疗相关，并且大多数改善在 4 周的随访中保持不变。

结论

研究结果为 UP 提供了初步的跨文化支持，并增加了越来越多的文献表明 UP 对非西方文化的低收入和中等收入国家的焦虑症患者有用。