mRNA vaccines have received major attention in the fight against COVID-19. Formulations from companies such as Moderna and BioNTech/Pfizer have allowed us to slowly ease the social distancing measures, mask requirements, and lockdowns that have been prevalent since early 2020. This past year’s focused work on mRNA vaccines has catapulted this technology to the forefront of public awareness and additional research pursuits, thus leading to new potential for bionanotechnology principles to help drive further innovation using mRNA. In addition to alleviating the burden of COVID-19, mRNA vaccines could potentially provide long-term solutions all over the world for diseases ranging from influenza to AIDS. Herein, we provide a brief commentary based on the history and development of mRNA vaccines in the context of the COVID-19 pandemic. Furthermore, we address current research using the technology and future directions of mRNA vaccine research.

mRNA 疫苗在对抗 COVID-19 的斗争中受到了广泛关注。来自 Moderna 和 BioNTech/Pfizer 等公司的配方使我们能够慢慢放宽自 2020 年初以来普遍存在的社交距离措施、口罩要求和封锁措施。去年对 mRNA 疫苗的重点工作使这项技术一跃成为最前沿的公众意识和额外的研究追求，从而导致生物纳米技术原理的新潜力，以帮助推动使用 mRNA 的进一步创新。除了减轻 COVID-19 的负担外，mRNA 疫苗还可能为全世界从流感到艾滋病等疾病提供长期解决方案。在此，我们根据 COVID-19 大流行背景下 mRNA 疫苗的历史和发展提供简要评论。此外，