Ensuring high coronavirus disease-2019 (COVID-19) vaccine uptake among US child care providers is crucial to mitigating the public health implications of child-staff and staff-child transmission of severe acute respiratory syndrome coronavirus 2; however, the vaccination rate among this group was previously unknown.

To characterize vaccine uptake among US child care providers, we conducted a multistate cross-sectional survey of the child care workforce. Providers were identified through various national databases and state registries. A link to the survey was sent via e-mail between May 26 and June 23, 2021. A 37.8% response yielded 21 663 respondents, with 20 013 satisfying inclusion criteria.

Overall COVID-19 vaccine uptake among US child care providers (78.2%, 90% confidence interval: 77.5% to 78.9%) was higher than the US general adult population (65%). Vaccination rates varied between states from 53.5% to 89.4%. Vaccine uptake among respondents differed significantly (P < .01) based on respondent age (70.0% for ages 25–34, 91.6% for ages 75–84), race (70.0% for Black or African Americans, 92.5% for Asian Americans), annual household income (70.8% for <$35 000, 85.1% for >$75 000), and child care setting (73.0% for home-based, 79.7% for center-based).

COVID-19 vaccine uptake among US child care providers was higher than the general US adult population. Those who were younger, lower income, Black or African American, resided in states either in the Mountain West or the South, and/or worked in home-based child care programs reported the lowest rates of vaccination. State public health leaders and lawmakers should prioritize these subgroups to realize the largest gains in vaccine uptake among providers.

确保美国儿童保育提供者大量接种 2019 冠状病毒病 (COVID-19) 疫苗，对于减轻严重急性呼吸综合征冠状病毒 2 型儿童与工作人员以及工作人员与儿童传播对公共卫生的影响至关重要；然而，该群体的疫苗接种率此前未知。

为了了解美国儿童保育提供者的疫苗接种情况，我们对儿童保育人员进行了一项多州横断面调查。提供者是通过各种国家数据库和州登记处确定的。该调查的链接于 2021 年 5 月 26 日至 6 月 23 日期间通过电子邮件发送。37.8% 的受访者中有 21 663 名受访者，其中 20 013 人满足纳入标准。

美国儿童保育提供者的总体 COVID-19 疫苗接种率（78.2%，90% 置信区间：77.5% 至 78.9%）高于美国一般成年人口（65%）。各州的疫苗接种率从 53.5% 到 89.4% 不等。根据受访者年龄（25-34 岁为 70.0%，75-84 岁为 91.6%）、种族（黑人或非裔美国人为 70.0%，亚裔美国人为 92.5%），受访者之间的疫苗接种率存在显着差异 ( P < .01) ）、家庭年收入（<$35 000 为 70.8%，>$75 000 为 85.1%），以及儿童保育环境（家庭为 73.0%，中心为 79.7%）。

美国儿童保育提供者对 COVID-19 疫苗的接种率高于美国一般成年人口。那些年龄较小、收入较低、黑人或非裔美国人、居住在西部山区或南部各州和/或在家庭儿童保育项目中工作的人报告的疫苗接种率最低。州公共卫生领导人和立法者应优先考虑这些亚组，以实现提供者疫苗接种率的最大收益。