Solvent separations present one of the largest opportunities for membrane technologies. Currently, industries use millions of tons of solvents for the manufacture of drugs, oils and chemicals. Multiple separations and purifications must be conducted in order to purify the products from the solvents. However, the existing separation processes are energy-intensive. Organic solvent nanofiltration (OSN) or solvent-resistant nanofiltration has emerged as an energy-efficient alternative to the existing processes. We have summarized the recent advances in the fabrication of state-of-the-art polymeric membranes including integrally skinned asymmetric membranes, thin film composite membranes and nanocomposite membranes in this review. The separation performances of OSN membranes continue to push the boundary in terms of high solvent permeances and rejections to various solutes. The advancements have been achieved through novel membrane materials and innovative fabrication methods. We have also discussed the future outlook of OSN processes and pointed out the potential areas for further research exploration.

溶剂分离是膜技术的最大机遇之一。目前，工业使用数百万吨的溶剂来制造药物、油和化学品。为了从溶剂中纯化产物，必须进行多次分离和纯化。然而，现有的分离过程是能源密集型的。有机溶剂纳滤 (OSN) 或耐溶剂纳滤已成为现有工艺的节能替代品。在这篇综述中，我们总结了制造最先进聚合物膜的最新进展，包括整体蒙皮不对称膜、薄膜复合膜和纳米复合膜。OSN 膜的分离性能在高溶剂渗透性和对各种溶质的截留率方面继续突破界限。这些进步是通过新型膜材料和创新制造方法实现的。我们还讨论了 OSN 过程的未来前景，并指出了进一步研究探索的潜在领域。