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MicroRNA-206 enhances antitumor immunity by disrupting the communication between malignant hepatocytes and regulatory T cells in c-Myc mice
Hepatology ( IF 12.9 ) Pub Date : 2021-10-04 , DOI: 10.1002/hep.32182
Ningning Liu 1 , Clifford J Steer 1, 2 , Guisheng Song 1, 2
Affiliation  

Intertumoral accumulation of regulatory T cells (Tregs) has been implicated in the pathogenesis of HCC. Because of poor understanding of the immunosuppression mechanism(s) in HCC, immunotherapy is largely unsuccessful for the treatment of HCC.

中文翻译:

MicroRNA-206 通过破坏 c-Myc 小鼠恶性肝细胞和调节性 T 细胞之间的通讯来增强抗肿瘤免疫

调节性 T 细胞 (Tregs) 的肿瘤间积累与 HCC 的发病机制有关。由于对 HCC 的免疫抑制机制了解甚少,因此免疫疗法在治疗 HCC 方面基本上是不成功的。
更新日期:2021-10-04
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