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Thorough QT Study to Evaluate the Effect of Zoliflodacin, a Novel Therapeutic for Gonorrhea, on Cardiac Repolarization in Healthy Adults
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-10-04 , DOI: 10.1128/aac.01292-21
Lori M Newman 1 , Martin Kankam 2 , Aya Nakamura 3 , Tom Conrad 3 , John Mueller 4 , John O'Donnell 4 , Blaire L Osborn 1 , Kenan Gu 1 , George A Saviolakis 5
Affiliation  

Zoliflodacin is a novel spiropyrimidinetrione antibiotic being developed as single oral dose treatment to address the growing global threat of Neisseria gonorrhoeae. To evaluate the cardiac safety of zoliflodacin, a thorough QT/QTc (TQT) study was ...

中文翻译:

全面的 QT 研究,以评估新型淋病治疗药物 Zoliflodacin 对健康成人心脏复极的影响

Zoliflodacin 是一种新型螺嘧啶三酮类抗生素,正在开发作为单次口服剂量治疗,以应对日益严重的全球淋病奈瑟菌威胁。为评估唑来氟达星的心脏安全性,一项彻底的 QT/QTc (TQT) 研究是...
更新日期:2021-10-06
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