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KPC-39-mediated resistance to Ceftazidime-Avibactam in a Klebsiella pneumoniae ST307 clinical isolate
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-10-04 , DOI: 10.1128/aac.01160-21
Agnès B Jousset 1, 2, 3, 4 , Saoussen Oueslati 1, 3 , Cécile Emeraud 1, 2, 3, 4 , Rémy A Bonnin 1, 2, 3 , Laurent Dortet 1, 2, 3, 4 , Bogdan I Iorga 5 , Thierry Naas 1, 2, 3, 4
Affiliation  

Resistance to ceftazidime–avibactam (CAZ-AVI) combination is being increasingly reported. Here, we report a CAZ-AVI resistant Klebsiella pneumoniae belonging to the high-risk ST307 clone and producing KPC-39, a single amino-acid variant of KPC-3 (A172T). ...

中文翻译:

KPC-39 介导的肺炎克雷伯菌 ST307 临床分离株对头孢他啶-阿维巴坦的耐药性

头孢他啶-阿维巴坦 (CAZ-AVI) 联合用药耐药的报道越来越多。在这里,我们报告了一种属于高风险 ST307 克隆并产生 KPC-39(KPC-3 (A172T) 的单个氨基酸变体)的耐 CAZ-AVI 肺炎克雷伯菌。...
更新日期:2021-10-06
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