当前位置: X-MOL 学术Chem. Pharm. Bull. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Immunochromatography—Application Example and POCT Type Genetic Testing
Chemical & Pharmaceutical Bulletin ( IF 1.5 ) Pub Date : 2021-10-01 , DOI: 10.1248/cpb.c21-00164
Isami Tsuboi 1 , Katsuhiro Iinuma 2
Affiliation  

Membrane-based rapid test reagents including immunochromatography are widely used in clinical practice. Recently, high-sensitive reagents based on the immunochromatography method, such as silver amplification method and time resolved fluorescence method for influenza testing, has been developed and early confirmation of infection can be achieved. Furthermore, genetic testing, automated all the steps from extraction till detection, is getting popular. Genetic testing of mycoplasma by Smart Gene Myco system and Coronavirus disease 2019 (COVID-19) test is a good example of membrane-based rapid test reagents. This system uses silica particle-containing membrane filter and enable to shorten the assay time by automates pre-treatment process for removing contamination substances in the sample which affect polymerase-chain-reaction amplification. We hope utilized genetic testing application will help quick confirmation of COVID-19 positive patient and prevent the collapse of medical system under COVID-19 development.

Fullsize Image


中文翻译:

免疫层析——应用实例和POCT型基因检测

包括免疫层析在内的基于膜的快速检测试剂在临床实践中得到广泛应用。近年来,基于免疫层析法的高灵敏度试剂,如银放大法和时间分辨荧光法等用于流感检测的试剂已经开发出来,可以实现感染的早期确认。此外,从提取到检测的所有步骤都自动化的基因检测越来越受欢迎。通过 Smart Gene Myco 系统和冠状病毒病 2019 (COVID-19) 测试对支原体进行基因检测是基于膜的快速检测试剂的一个很好的例子。该系统使用含二氧化硅颗粒的膜过滤器,通过自动化预处理过程来去除样品中影响聚合酶链反应扩增的污染物质,从而缩短分析时间。

全尺寸图像
更新日期:2021-10-14
down
wechat
bug