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Large-scale provocation studies identify maladaptive responses to ubiquitous aeroallergens as a correlate of severe allergic rhinoconjunctivitis and asthma
Allergy ( IF 12.6 ) Pub Date : 2021-10-04 , DOI: 10.1111/all.15124
Alisha M Smith 1, 2, 3, 4 , Robert M Ramirez 5 , Nathan Harper 1, 2 , Fabio Jimenez 1, 2 , Anne P Branum 1, 2 , Justin A Meunier 1, 2 , Lavanya Pandranki 1, 4 , Andrew Carrillo 1, 2, 4 , Caitlyn Winter 1, 6 , Lauryn Winter 1, 6 , Cynthia G Rather 5 , Daniel A Ramirez 5 , Charles P Andrews 5 , Marcos I Restrepo 1, 4 , Diego J Maselli 1, 4 , Jacqueline A Pugh 1 , Robert A Clark 1, 2, 3, 4 , Grace C Lee 1, 7, 8 , Alvaro G Moreira 1, 9 , Muthu Saravanan Manoharan 1, 4 , Jason F Okulicz 10 , Robert L Jacobs 5 , Sunil K Ahuja 1, 2, 3, 4, 11
Affiliation  

Allergic asthma (AA) and allergic rhinoconjunctivitis (ARC) are common comorbid environmentally triggered diseases. We hypothesized that severe AA/ARC reflects a maladaptive or unrestrained response to ubiquitous aeroallergens.

中文翻译:

大规模激发研究确定对普遍存在的气源性过敏原的适应不良反应与严重过敏性鼻结膜炎和哮喘有关

过敏性哮喘 (AA) 和过敏性鼻结膜炎 (ARC) 是常见的环境诱发疾病。我们假设严重的 AA/ARC 反映了对普遍存在的气源性过敏原的适应不良或无节制的反应。
更新日期:2021-10-04
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