Lacrimal gland inflammation has been identified as an important limitation on aqueous production and associated dry eye disease. Ocular surface inflammation in dry eye disease can be a downstream response to reduced quantities of warmer hyperosmotic aqueous being delivered from an inflamed lacrimal gland with high concentrations of inflammatory mediators. This review examines evidence which shows how topical applications of anti-inflammatory drugs have very limited access to the lacrimal gland and an associated limited capacity to increase aqueous flow by reducing inflammation in the main lacrimal gland.

中文翻译：

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房水不足的透皮抗炎治疗

泪腺炎症已被确定为对房水产生和相关干眼病的重要限制。干眼病中的眼表炎症可能是对从具有高浓度炎症介质的发炎泪腺输送的高渗性房水量减少的下游反应。本综述审查的证据表明，局部应用抗炎药物对泪腺的进入非常有限，并且通过减少主要泪腺的炎症来增加房水流量的相关能力有限。