Abstract

Recently, it has become more and more obvious that the use of the unique physical properties of graphene is practically inexhaustible. In our work, we used the surface of oxygen-free graphene sheets to stabilize the AlClPc complex and prevent its agglomeration. A sonochemical method was developed for the preparation of stable suspensions of oxygen-free graphene in a DMF-aqua mixture, the composition and morphology of which were characterized using TEM, DLS, and Raman. Also, a method for the synthesis of hybrid structures based on AlClPc and graphene was developed, and new electrons interactions in them were determined by using of UV-VIS absorption spectroscopy. It was proved that these interactions are due to the graphene participation in surface complex with charge transfer. Graphene also prevents the agglomeration of the AlClPc complex, which is especially valuable for using the synthesized structure in biomedical research. The results obtained show how the use of molecular design techniques makes it possible to create new platforms for vector drag delivery and early diagnosis.

摘要

最近越来越明显的是，利用石墨烯独特的物理特性实际上是取之不尽用之不竭的。在我们的工作中，我们使用无氧石墨烯片的表面来稳定 AlClPc 复合物并防止其团聚。开发了一种用于在 DMF-aqua 混合物中制备稳定的无氧石墨烯悬浮液的声化学方法，使用 TEM、DLS 和拉曼表征其组成和形态。此外，还开发了一种基于 AlClPc 和石墨烯的杂化结构合成方法，并利用 UV-VIS 吸收光谱确定了其中的新电子相互作用。事实证明，这些相互作用是由于石墨烯参与了表面配合物的电荷转移。石墨烯还可以防止 AlClPc 复合物的团聚，这对于在生物医学研究中使用合成结构特别有价值。获得的结果表明，分子设计技术的使用如何使创建用于载体药物递送和早期诊断的新平台成为可能。