An Ir/Cu bimetallic relay catalysis was developed to achieve the challenging asymmetric deoxygenative alkynylation of inert amides under mild conditions, affording a series of synthetically important chiral propargylamines in high yields with good to excellent enantioselectivities.

中文翻译：

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通过铱/铜双金属继电器催化实现叔酰胺的不对称脱氧炔化

开发了一种 Ir/Cu 双金属继电器催化，以在温和条件下实现惰性酰胺的具有挑战性的不对称脱氧炔化，以高产率提供一系列具有良好至优异对映选择性的合成重要手性炔丙基胺。