The selenium (Se)-containing imidazole compound selenoneine (2-selenyl-N_α, N_α, N_α-trimethyl-l-histidine) is a strong scavenger of reactive oxygen species (ROS) in the blood and tissues of fish. Intravenous injection of selenoneine into yellowtail has been shown to delay changes in meat color and prevent met-myoglobin formation in red muscle. In this study, to determine whether selenoneine can improve stress tolerance and meat quality in fish, we examined the biological antioxidant functions of selenoneine in fish in vivo. Juvenile amberjack (Seriola dumerili) were cultured and fed a diet containing selenoneine for 9 weeks. Total Se and selenoneine concentrations increased in amberjack blood and muscles during the study period. We also measured the oxidative–redox potential (ORP) in fish muscle using an ORP electrode and found that muscle ORP and ROS levels were closely correlated with the Se concentration in blood and muscles. We conclude that dietary administration of selenoneine led to its accumulation in amberjack blood and muscles, resulting in reduced ORP and ROS levels in the muscles.

含硒 (Se) 的咪唑化合物硒酮 (2-selenyl- N _α , N _α , N _α -trimethyl - l- histidine) 是鱼类血液和组织中活性氧 (ROS) 的强清除剂。已证明向黄尾鱼静脉注射硒酮素可延缓肉色变化并防止红肌中高铁肌红蛋白的形成。在这项研究中，为了确定硒酮是否可以改善鱼类的应激耐受性和肉质，我们在体内检测了硒酮在鱼体内的生物抗氧化功能。少年琥珀鱼 ( Seriola dumerili) 被培养并喂食含有硒酮的饮食 9 周。在研究期间，琥珀鱼血液和肌肉中的总硒和硒氨酸浓度增加。我们还使用 ORP 电极测量了鱼肌肉中的氧化还原电位 (ORP)，发现肌肉 ORP 和 ROS 水平与血液和肌肉中的硒浓度密切相关。我们得出结论，硒酮的饮食管理导致其在琥珀鱼血液和肌肉中的积累，导致肌肉中的 ORP 和 ROS 水平降低。