Room-temperature growth of covalent organic frameworks as the stationary phase for open-tubular capillary electrochromatography,Analyst

当前位置： X-MOL 学术 › Analyst › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Room-temperature growth of covalent organic frameworks as the stationary phase for open-tubular capillary electrochromatography
Analyst ( IF 3.6 ) Pub Date : 2021-09-06 , DOI: 10.1039/d1an01402a
Qiaoyan Li _{1,

2} , Zhentao Li _{1,

2} , Yuanyuan Fu ₁ , Igor Clarot ₃ , Ariane Boudier ₃ , Zilin Chen _{1,

2}

Affiliation

Covalent organic frameworks (COFs) are a class of porous materials with high surface area, high porosity, good stability and tunable structure that have been widely used in the separation area. In this work, we have proposed the in situ synthesis of a novel COF composed of 4,4′,4′′-(1,3,5-triazine-2,4,6-triyl)trianiline (Tz) and 1,4-dihydroxyterephthalaldehyde (Da) onto the capillary inner surface for electrochromatographic separation. Fourier transform infrared (FT-IR) spectroscopy, elemental analysis (EA) and scanning electron microscopy (SEM) have facilitated the characterization of the prepared capillary columns. The COF (TzDa) modified OT-CEC column exhibited satisfactory separation selectivity towards neutral compounds (such as chlorobenzenes and alkylbenzenes), acidic and basic compounds (such as phenols and anilines), food additives (vanillin and its analogues) and small biomolecules (such as amino acids and polypeptides). Furthermore, the TzDa modified capillary was quite stable and reproducible. The relative standard deviations for retention times of the test analytes (alkylbenzenes) were as follows: for intra-day (n = 3) runs (≤1.74%), inter-day (n = 3) runs (≤2.25%) and between columns (n = 3) (≤4.83%). This new type of COF-based stationary phase has tremendous potential in separation science.

中文翻译：

作为开管毛细管电色谱固定相的共价有机骨架的室温生长

共价有机骨架（COFs）是一类具有高比表面积、高孔隙率、稳定性好、结构可调的多孔材料，已广泛应用于分离领域。在这项工作中，我们提出了原位在毛细管内部合成由 4,4',4''-(1,3,5-triazine-2,4,6-triyl)trianiline (Tz) 和 1,4-二羟基对苯二醛 (Da) 组成的新型 COF用于电色谱分离的表面。傅里叶变换红外 (FT-IR) 光谱、元素分析 (EA) 和扫描电子显微镜 (SEM) 有助于表征制备的毛细管柱。COF (TzDa) 修饰的 OT-CEC 色谱柱对中性化合物（如氯苯和烷基苯）、酸性和碱性化合物（如酚类和苯胺）、食品添加剂（香兰素及其类似物）和小生物分子（如如氨基酸和多肽）。此外，TzDa 改性毛细管非常稳定且可重现。n = 3) 运行 (≤1.74%)、日间 ( n = 3) 运行 (≤2.25%) 和列之间 ( n = 3) (≤4.83%)。这种新型的基于 COF 的固定相在分离科学中具有巨大的潜力。

更新日期：2021-10-01

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11