Pyronaridine-Artesunate (Pyramax®) for the Treatment of Artemisinin- and Piperaquine-Resistant Plasmodium falciparum in the Central Highlands of Vietnam,Antimicrobial Agents and Chemotherapy

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Pyronaridine-Artesunate (Pyramax®) for the Treatment of Artemisinin- and Piperaquine-Resistant Plasmodium falciparum in the Central Highlands of Vietnam
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-09-27 , DOI: 10.1128/aac.00276-21
Nguyen Duc Manh ₁ , Nguyen Van Thanh ₁ , Huynh Hong Quang ₂ , Nguyen Thi Thanh Van ₁ , Nguyen Ngoc San ₁ , Nguyen Chinh Phong ₁ , Geoffrey W Birrell ₃ , Michael D Edstein ₃ , Kimberly A Edgel ₄ , Nicholas J Martin ₄ , Marina Chavchich ₃

Affiliation

The rise in Plasmodium falciparum resistance to dihydroartemisinin-piperaquine in Vietnam justifies the need to evaluate alternative artemisinin-based combination therapies. Between July 2018 and October 2019, a single-arm trial of pyronaridine-artesunate ...

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