Pancreatic cancer is one of the most aggressive and lethal malignant neoplasms in the world and 5-year survival rate still remains below 10%. Although, there are many reasons for that, one definitely is the lack of early and unique diagnostic tools for pancreatic cancer screening, which somehow correlates with no sufficient knowledge about cancer’s molecular nature. This article aims to prove the concept that an application of molecular spectroscopic methods including FTIR hyperspectral imaging and Raman hyperspectral mapping, combined with proper tissue pre-processing and analytical algorithms, allows differentiating benign and malignant pancreatic glands with good precision.

胰腺癌是世界上最具侵袭性和致命性的恶性肿瘤之一，5年生存率仍低于10%。尽管有很多原因，其中一个肯定是缺乏用于胰腺癌筛查的早期和独特的诊断工具，这在某种程度上与对癌症的分子性质没有足够的了解有关。本文旨在证明包括 FTIR 高光谱成像和拉曼高光谱绘图在内的分子光谱方法的应用，结合适当的组织预处理和分析算法，可以以良好的精度区分良恶性胰腺的概念。