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A multifunctional green antibacterial rapid hemostasis composite wound dressing for wound healing
Biomaterials Science ( IF 5.8 ) Pub Date : 2021-09-21 , DOI: 10.1039/d1bm01185e Wencheng Liang 1, 2 , Qiaohui Lu 3 , Fan Yu 4 , Junyong Zhang 1 , Chuang Xiao 1 , Xiaoming Dou 2 , Yan Zhou 3 , Xiumei Mo 4 , Jun Li 5 , Meidong Lang 1
Biomaterials Science ( IF 5.8 ) Pub Date : 2021-09-21 , DOI: 10.1039/d1bm01185e Wencheng Liang 1, 2 , Qiaohui Lu 3 , Fan Yu 4 , Junyong Zhang 1 , Chuang Xiao 1 , Xiaoming Dou 2 , Yan Zhou 3 , Xiumei Mo 4 , Jun Li 5 , Meidong Lang 1
Affiliation
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Rapid hemostasis and antibacterial properties are essential for novel wound dressings to promote wound healing. In particular, timely and rapid hemostasis could be of benefit to reduce the mortality caused by excessive bleeding loss. Herein, we present a novel strategy of combining electrospinning technology with post-modification technology to prepare a multifunctional wound dressing, cellulose diacetate-based composite wound dressing (CDCE), with rapid hemostasis and antibacterial activity. It is interesting that the CDCE wound dressing had superhydrophilicity, high water absorption, and strong absorbing capacity, which could eliminate the exudate around the wound in a timely manner and further promote rapid hemostasis. Additionally, its excellent antibacterial properties could inhibit severe infection in the wound and accelerate wound healing. Based on these advantages, the novel CDCE wound dressing could promote wound contraction and further accelerate wound healing compared with the common traditional wound dressing gauze. Taken together, the multifunctional CDCE wound dressing has high potential for clinical application in the future.
中文翻译：
一种用于伤口愈合的多功能绿色抗菌快速止血复合伤口敷料
快速止血和抗菌特性对于新型伤口敷料促进伤口愈合至关重要。尤其是及时快速止血可能有助于降低因失血过多导致的死亡率。在此，我们提出了一种将静电纺丝技术与后修饰技术相结合的新策略，以制备具有快速止血和抗菌活性的多功能伤口敷料，二醋酸纤维素基复合伤口敷料（CDCE）。有趣的是，CDCE伤口敷料具有超亲水性、高吸水性和强吸收能力，可以及时清除伤口周围的渗出液，进一步促进快速止血。此外，其优异的抗菌性能可以抑制伤口的严重感染，加速伤口愈合。基于这些优点，与普通的传统伤口敷料纱布相比，新型CDCE伤口敷料可以促进伤口收缩，进一步加速伤口愈合。综上所述，多功能CDCE伤口敷料在未来具有很高的临床应用潜力。
更新日期：2021-09-28
中文翻译：
一种用于伤口愈合的多功能绿色抗菌快速止血复合伤口敷料
快速止血和抗菌特性对于新型伤口敷料促进伤口愈合至关重要。尤其是及时快速止血可能有助于降低因失血过多导致的死亡率。在此，我们提出了一种将静电纺丝技术与后修饰技术相结合的新策略，以制备具有快速止血和抗菌活性的多功能伤口敷料，二醋酸纤维素基复合伤口敷料（CDCE）。有趣的是，CDCE伤口敷料具有超亲水性、高吸水性和强吸收能力，可以及时清除伤口周围的渗出液，进一步促进快速止血。此外，其优异的抗菌性能可以抑制伤口的严重感染，加速伤口愈合。基于这些优点，与普通的传统伤口敷料纱布相比，新型CDCE伤口敷料可以促进伤口收缩，进一步加速伤口愈合。综上所述，多功能CDCE伤口敷料在未来具有很高的临床应用潜力。
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