Regulatory roles of three miRNAs on allergen mRNA expression in Tyrophagus putrescentiae,Allergy

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Regulatory roles of three miRNAs on allergen mRNA expression in Tyrophagus putrescentiae
Allergy ( IF 12.6 ) Pub Date : 2021-09-27 , DOI: 10.1111/all.15111
Ying Zhou ₁ , Qingqing Li ₂ , Ruilin Pan ₂ , Qiong Wang ₂ , Xuming Zhu ₂ , Cunyin Yuan ₂ , Fangfang Cai ₂ , Ya-Dong Gao ₃ , Yubao Cui ₂

Affiliation

Tyrophagus putresecentiae is an important mite species in rural and urban environments, causing sensitization and allergic disease. While evidence suggests that microRNAs (miRNAs) may regulate the expression of allergen-encoding genes, no study has directly investigated this possibility. Here, this gap was addressed by profiling miRNAs and elucidating their target allergen messenger RNAs (mRNAs) in this mite species.

中文翻译：

三种 miRNA 对腐食菌过敏原 mRNA 表达的调控作用

Tyrophagus putresecentiae是农村和城市环境中的重要螨种，引起致敏和过敏性疾病。虽然有证据表明 microRNA (miRNA) 可以调节过敏原编码基因的表达，但没有研究直接调查过这种可能性。在这里，通过分析 miRNA 并阐明其在该螨物种中的目标过敏原信使 RNA (mRNA) 来解决这一差距。

更新日期：2021-09-27

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