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Identification of fetal aneuploidy with dual-probe fluorescence in situ hybridization analysis in circulating trophoblasts after enrichment using a high-sensitivity microfluidic platform
Prenatal Diagnosis ( IF 2.7 ) Pub Date : 2021-09-28 , DOI: 10.1002/pd.6046
Jiri Sonek 1 , Rolf Muller 2 , Judy Muller-Cohn 2 , Janet Dickerson 2 , Brenda Garcia Lopez 2 , Jennifer Barber-Singh 2 , Dylan Dufek 2 , Adam Kinney Hiett 1 , Philip Buchanan 3
Affiliation  

To evaluate a microfluidics-based positive selection technology for isolating circulating trophoblasts (CTs) from peripheral blood of women whose pregnancies are affected by aneuploidy and to evaluate fetal karyotype using fluorescence in situ hybridization (FISH).

中文翻译:

高灵敏度微流控平台富集后循环滋养细胞双探针荧光原位杂交分析鉴定胎儿非整倍性

评估一种基于微流体的阳性选择技术,用于从受非整倍体影响的妊娠妇女外周血中分离循环滋养细胞 (CT),并使用荧光原位杂交 (FISH) 评估胎儿核型。
更新日期:2021-09-28
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