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Thyroid Eye Disease Following COVID-19 Vaccine in a Patient With a History Graves' Disease: A Case Report.
Ophthalmic Plastic and Reconstructive Surgery ( IF 1.2 ) Pub Date : 2021-09-24 , DOI: 10.1097/iop.0000000000002059
Tal J Rubinstein 1, 2, 3
Affiliation  

A 50-year-old woman with a history of controlled Graves' disease without clinical ophthalmopathy presents with 2 months of left more than right periorbital swelling and proptosis. Her eye symptoms and signs began 3 days following her second vaccination against the COVID-19 virus. Orbital imaging, elevated thyroid stimulating immunoglobulin, and negative systemic work up for other diseases were consistent with a diagnosis of active thyroid eye disease. The temporal relationship to her vaccination was likely consistent with autoimmune/inflammatory syndrome associated with adjuvants. Clinicians should remind patients of the symptoms and signs of thyroid eye disease and to seek appropriate medical and ophthalmic advice if they occur after the COVID-19 vaccine.

中文翻译:


有格雷夫斯病病史的患者接种 COVID-19 疫苗后出现甲状腺眼病:病例报告。



一名 50 岁女性,有格雷夫斯病控制史,无临床眼病,表现为左眼眶周围肿胀和突眼持续 2 个月多于右眼。她的眼部症状和体征在她第二次接种 COVID-19 病毒疫苗后 3 天开始出现。眼眶成像、甲状腺刺激免疫球蛋白升高以及其他疾病的阴性全身检查均与活动性甲状腺眼病的诊断一致。她接种疫苗的时间关系可能与佐剂相关的自身免疫/炎症综合征一致。临床医生应提醒患者甲状腺眼病的症状和体征,如果在接种 COVID-19 疫苗后出现此类症状和体征,应寻求适当的医疗和眼科建议。
更新日期:2021-09-24
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