Our previous work established a continuous-flow synthesis of pristane, which is a saturated branched alkane obtained from a Basking Shark. The dehydration of an allylic alcohol that is the key to a tetraene was carried out using a packed-bed reactor charged by an acid–silica catalyst (HO-SAS) and flow hydrogenation using molecular hydrogen via a Pd/C catalyst followed. The present work relies on the additional propensity of Pd/C to serve as an acid catalyst, which allows us to perform a flow synthesis of pristane from the aforementioned key allylic alcohol in the presence of molecular hydrogen using Pd/C as a single catalyst, which is applied to both dehydration and hydrogenation. The present one-column-two-reaction-flow system could eliminate the use of an acid catalyst such as HO-SAS and lead to a significant simplification of the production process.

中文翻译：

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使用以 Pd/C 作为单一催化剂的填充床反应器通过烯丙醇的流动脱水加氢更绿色地合成 Pristane

我们之前的工作建立了一种连续流动合成的 prisane，这是一种从 Basking Shark 获得的饱和支链烷烃。使用由酸-二氧化硅催化剂（HO-SAS）填充的填充床反应器进行四烯关键烯丙醇的脱水，然后通过 Pd/C 催化剂使用分子氢进行流动氢化。目前的工作依赖于 Pd/C 作为酸催化剂的额外倾向，这使我们能够在分子氢的存在下使用 Pd/C 作为单一催化剂，从上述关键烯丙醇中进行丙烷的流动合成，适用于脱水和加氢。