ABSTRACT

Background

Stroke is aleading cause of death and disability, with atrial fibrillation (AF) being among key risk factors and AF-related stroke inflicting significant burden on healthcare systems and society. The present study was undertaken for estimating the total annual socioeconomic burden of AF-related stroke in Greece and identifying the key cost contributors.

Research design and methods

A cost-of-illness model was developed for estimating the total annual economic burden of AF-related stroke in Greece, from asocietal perspective (year 2018). Atargeted literature review and an advisory board consisting of key experts in the management of AF and AF-related stroke were performed for collecting local resource use and epidemiological data.

Results

The total annual socioeconomic burden of AF-related stroke was estimated at €175million, in 2018. Direct and indirect costs accounted for 59% and 41%, respectively. Main contributors were informal care (21.1%), patients’ productivity losses (19.7%) and hospitalizations (15.0%), accounting for more than half of the total costs of AF-related stroke events.

Conclusion: A F-related stroke imposes asignificant socioeconomic burden in Greece. Despite results relying on estimations, it seems that ensuring efficient reallocation of resources in appropriate prevention and early intervention strategies could decrease AF-related stroke’s burden but also enhance healthcare systems’ efficiency.

Abbreviations

AF=atrial fibrillation

中文翻译：

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希腊房颤相关卒中的经济负担估计

摘要

背景

中风是导致死亡和残疾的主要原因，房颤 (AF) 是主要危险因素之一，与 AF 相关的中风给医疗保健系统和社会带来重大负担。本研究旨在估计希腊 AF 相关卒中的年度社会经济总负担，并确定主要成本贡献者。

研究设计与方法

开发了一个疾病成本模型，用于从社会角度（2018 年）估计希腊 AF 相关卒中的年度总经济负担。进行了有针对性的文献回顾和由 AF 和 AF 相关卒中管理的主要专家组成的咨询委员会，以收集当地资源使用和流行病学数据。

结果

2018 年，AF 相关卒中的年度社会经济总负担估计为 1.75 亿欧元。直接和间接成本分别占 59% 和 41%。主要贡献者是非正式护理 (21.1%)、患者生产力损失 (19.7%) 和住院 (15.0%)，占 AF 相关卒中事件总成本的一半以上。

结论：与 F 相关的中风给希腊带来了巨大的社会经济负担。尽管结果依赖于估计，但似乎确保在适当的预防和早期干预策略中有效地重新分配资源可以减少 AF 相关中风的负担，但也可以提高医疗保健系统的效率。

缩写

AF=心房颤动