Background and Objectives

To assess gender differences in prevalence of neuropsychiatric symptoms (NPS) among community-dwelling Mexican Americans ≥80 years. Research Design and Methods: Using data from Wave 7 (2010–2011) of the Hispanic Established Population for the Epidemiological Study of the Elderly, we analyzed the NPS of 914 participants as determined by the Neuropsychiatric Inventory (NPI) with assessments conducted by their caregivers. Multivariate logistic regression models were used to test the association of individual NPS with gender, adjusting for relevant characteristics. Results: The average age of our sample was 86.1 years, and 65.3% were women. Over 60% of participants had at least one informant/caregiver reported NPS. After adjustment, women had lower odds than men of agitation/aggression but higher odds of dysphoria/depression and anxiety. Discussion: Recognizing gender differences in NPS phenotype could help guide development of culturally appropriate NPS screening and treatment programs.

背景和目标

评估 80 岁以上居住在社区的墨西哥裔美国人中神经精神症状 (NPS) 患病率的性别差异。研究设计和方法：使用第 7 波（2010-2011 年）西班牙裔老年人流行病学研究的数据，我们分析了 914 名参与者的 NPS，由神经精神病学清单 (NPI) 确定，并由他们的护理人员进行评估. 多变量逻辑回归模型用于测试个体 NPS 与性别的关联，并针对相关特征进行调整。结果：我们样本的平均年龄为 86.1 岁，其中 65.3% 是女性。超过 60% 的参与者至少有一名线人/护理人员报告了 NPS。调整后，女性比男性躁动/攻击性低，但烦躁/抑郁和焦虑的几率更高。讨论：认识到 NPS 表型的性别差异有助于指导制定适合文化的 NPS 筛查和治疗计划。