Neopentyl glycol (NPG) is a precursor for the manufacture of many valuable products of industrial importance such as polyester, polyurethane and alkyd resins, synthetic lubricants, hydraulic fluids, drugs, etc. The structure of NPG provides the resins with excellent hydrolytic stability, resistance to weather conditions, good flexibility-hardness balance, and outstanding functional properties. The paper presents a literature review on the development of methods for NPG preparation, focusing primarily on the synthesis of NPG by hydrogenation of hydroxypivaldehyde, which is obtained by the crossed aldol condensation of isobutyraldehyde and formaldehyde. Preparation of the substrates, catalysts, technical and apparatus solutions, and NPG purification were discussed.

中文翻译：

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羟基新戊醛加氢合成新戊二醇的方法开发

新戊二醇 (NPG) 是制造许多具有工业重要性的有价值产品的前体，例如聚酯、聚氨酯和醇酸树脂、合成润滑剂、液压油、药物等。 NPG 的结构为树脂提供了优异的水解稳定性、抗性适应气候条件、良好的柔韧性-硬度平衡和出色的功能特性。本文对 NPG 制备方法的发展进行了文献综述，主要关注通过异丁醛和甲醛的交叉羟醛缩合获得的羟基新戊醛的氢化合成 NPG。讨论了底物的制备、催化剂、技术和设备解决方案以及 NPG 纯化。