Forging C−S Bonds Through Decarbonylation: New Perspectives for the Synthesis of Privileged Aryl Sulfides,ChemCatChem

当前位置： X-MOL 学术 › ChemCatChem › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Forging C−S Bonds Through Decarbonylation: New Perspectives for the Synthesis of Privileged Aryl Sulfides
ChemCatChem ( IF 3.8 ) Pub Date : 2021-09-25 , DOI: 10.1002/cctc.202101206
Chengwei Liu ₁ , Michal Szostak ₂

Affiliation

Cross-Coupling: Aryl thioethers represent one of the most important moieties in chemical science, ranging from polymers through functional materials to pharmaceuticals. Recently a series of reports has advanced an alternative cross-coupling manifold in which thio(esters) are subject to transition-metal-catalyzed intramolecular decarbonylation. These emerging technologies address challenges encountered during the traditional synthesis and permit to directly install aryl thioethers on complex APIs, thus advancing horizons for novel previously unattainable synthetic disconnections and introducing new concepts in catalysis.

中文翻译：

通过脱羰基形成 C−S 键：合成特殊芳基硫醚的新视角

交叉偶联：芳基硫醚代表化学科学中最重要的部分之一，范围从聚合物到功能材料再到药物。最近一系列的报道提出了一种替代的交叉偶联流形，其中硫代（酯）进行过渡金属催化的分子内脱羰。这些新兴技术解决了传统合成过程中遇到的挑战，并允许将芳基硫醚直接安装在复杂的 API 上，从而推进了以前无法实现的新型合成断开的视野，并引入了催化领域的新概念。

更新日期：2021-09-25

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11