Background:To compare the detection rate of micro-ultrasound with multiparametric magnetic resonance imaging targeted biopsy (mpMRI-TB) for prostate cancer diagnosis. Methods: The studies on micro-ultrasound prostate biopsy for prostate cancer diagnosis were searched in PubMed, Cochrane library and EMBASE databases from inception to April.2021. we performed a systematic review and cumulative meta-analysis based on search results using Software Rev-Man 5.3. Results: A total of 11 studies involving 1081 patients were included. The Meta-analysis showed that no significant difference was found between micro-ultrasound and mpMRI-TB in the total detection of prostate cancer(OR:1.01, 95%CI:0.85~1.21, p=0.89), of Grading Groups(GG)=1(OR: 0.92, 95%CI:0.68~1.25, p=0.59),of GG≥2(OR:1.01, 95%CI:0.83~1.22, p=0.92), and of GG≥3(OR: 1.31, 95%CI:0.95~1.81, p=0.10). Conclusions: Micro-ultrasound guided prostate biopsy provides comparable detection rates for prostate cancer diagnosis with the mpMRI-TB, which is expected to challenge mpMRI-TB in the diagnosis of prostate cancer.

中文翻译：

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微超声引导下前列腺活检检测前列腺癌：系统评价和荟萃分析

背景：比较微超声与多参数磁共振成像靶向活检（mpMRI-TB）在前列腺癌诊断中的检出率。方法：在 PubMed、Cochrane 图书馆和 EMBASE 数据库中检索从成立到 2021 年 4 月的微超声前列腺活检用于前列腺癌诊断的研究。我们使用 Software Rev-Man 5.3 根据搜索结果进行了系统回顾和累积荟萃分析。结果：共纳入 11 项研究，涉及 1081 名患者。Meta分析显示，各分级组（GG）的前列腺癌总检出率（OR：1.01，95%CI：0.85~1.21，p=0.89）与微超声和mpMRI-TB无显着差异。 =1(OR: 0.92, 95%CI:0.68~1.25, p=0.59), GG≥2(OR:1.01, 95%CI:0.83~1.22, p=0.92), GG≥3(OR: 1.31，95%CI：0.95~1.81，p=0。10）。结论：微超声引导下的前列腺活检提供了与 mpMRI-TB 相当的前列腺癌诊断检出率，这有望在前列腺癌的诊断中挑战 mpMRI-TB。