A pair of new 3′,7-epoxy-8,4′-oxyneolignan enantiomers [(+)-1 and (−)-1] as well as a known phenylpropanoid (2) were isolated from the seeds of Croton tiglium Linn. Their structures were established based on extensive spectroscopic analyses. The absolute configurations of (+)-1 and (−)-1 were determined by NMR data calculations and electronic circular dichroism calculations. All compounds were isolated from the genus Croton for the first time. Particularly, (+)-1 and (−)-1 were the first 3′,7-epoxy-8,4′-oxyneolignanes reported in Croton. The chemotaxonomic significance of these compounds was discussed.

从Croton tiglium Linn的种子中分离出一对新的 3',7-epoxy-8,4'-oxyneolignan 对映体 [(+)- 1和 (-)- 1 ] 以及一种已知的苯丙烷 ( 2 ) 。它们的结构是基于广泛的光谱分析建立的。(+)- 1和(-)- 1的绝对构型通过NMR数据计算和电子圆二色性计算确定。所有化合物均为首次从巴豆属中分离得到。特别是，(+)- 1和 (-)- 1是第一个在巴豆报道的 3',7-epoxy-8,4'-oxyneolignanes. 讨论了这些化合物的化学分类学意义。