The aim of this review or meta-analysis is to synthesize the prevalence of post-coronavirus disease (COVID) pain symptoms of musculoskeletal origin in hospitalized or nonhospitalized patients recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. MEDLINE, CINAHL, PubMed, EMBASE, and Web of Science databases, as well as medRxiv and bioRxiv preprint servers were searched up to May 1, 2021. Studies or preprints reporting data on post-COVID pain symptoms such as myalgias, arthralgias, or chest pain after SARS-CoV-2 infection and collected by personal, telephonic, or electronical interview were included. The methodological quality of the studies was assessed using the Newcastle–Ottawa Scale. Random-effects models were used for meta-analytical pooled prevalence of each post-COVID musculoskeletal pain symptom. Data synthesis was categorized at onset or hospital admission and at 30, 60, and 90, and ≥180 days after. From a total of 12,123 studies identified, 27 peer-reviewed studies and 6 preprints were included. The sample included 14,639 hospitalized and 11,070 nonhospitalized COVID-19 patients. The methodological quality of almost 70% studies was fair. The overall prevalence of post-COVID myalgia, joint pain, and chest pain ranged from 5.65% to 18.15%, 4.6% to 12.1%, and 7.8% to 23.6%, respectively, at different follow-up periods during the first year postinfection. Time trend analysis showed a decrease prevalence of musculoskeletal post-COVID pain from the symptom's onset to 30 days after, an increase 60 days after, but with a second decrease ≥180 days after. This meta-analysis has shown that almost 10% of individuals infected by SARS-CoV-2 will suffer from musculoskeletal post-COVID pain symptomatology at some time during the first year after the infection.

本综述或荟萃分析的目的是综合从严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 感染中康复的住院或非住院患者中肌肉骨骼来源的冠状病毒后疾病 (COVID) 疼痛症状的患病率。搜索了截至 2021 年 5 月 1 日的 MEDLINE、CINAHL、PubMed、EMBASE 和 Web of Science 数据库，以及 medRxiv 和 bioRxiv 预印本服务器。研究或预印本报告了有关 COVID 后疼痛症状（如肌痛、关节痛或胸部）的数据包括通过个人、电话或电子采访收集的 SARS-CoV-2 感染后的疼痛。使用纽卡斯尔-渥太华量表评估研究的方法学质量。随机效应模型用于荟萃分析汇总患病率每个 COVID 后的肌肉骨骼疼痛症状。数据合成在发病或入院时以及 30、60、90 和 ≥180 天后进行分类。从总共确定的 12,123 项研究中，包括 27 项同行评审研究和 6 项预印本。样本包括 14,639 名住院和 11,070 名非住院 COVID-19 患者。几乎 70% 的研究的方法学质量是公平的。在感染后第一年的不同随访期间，COVID 后肌痛、关节痛和胸痛的总体患病率分别为 5.65% 至 18.15%、4.6% 至 12.1% 和 7.8% 至 23.6%。时间趋势分析显示患病率下降COVID 后肌肉骨骼疼痛从症状发作到 30 天，在 60 天后增加，但在 ≥180 天后第二次减少。这项荟萃分析表明，在感染后第一年的某个时间，几乎 10% 的 SARS-CoV-2 感染者会出现肌肉骨骼疼痛症状。