Pseudallescheria keratitis is rare but important type of fungal keratitis because of the inherently resistance of the organism to many existing antifungal agents. Slit-lamp and confocal microscopy were used for clinical examinations. Fungal isolates were identified based on morphological characteristics and DNA sequence of the internal transcribed spacer region (ITS). In vitro antifungal susceptibility testing for fungal isolates was performed according to the Clinical and Laboratory Standards Institute (CLSI, M38-A2). All patients had a history of ocular trauma. In clinical examination hypopion were seen in three patients. The main antifungal medications were topical voriconazole. After treatment the visual acuity of all patients improved in 2–3 weeks. All four patients of Pseudallescheria keratitis had similar clinical features. Accurate and rapid identification of species should be helpful in treating p. boydii keratitis.

中文翻译：

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Pseudallescheria boydii 引起的真菌性角膜炎：临床和真菌学特征

Pseudallescheria keratitis 是一种罕见但重要的真菌性角膜炎，因为该生物体对许多现有的抗真菌剂具有固有的抗性。裂隙灯和共聚焦显微镜用于临床检查。根据内部转录间隔区 (ITS) 的形态特征和 DNA 序列鉴定真菌分离株。根据临床和实验室标准协会 (CLSI, M38-A2) 对真菌分离株进行体外抗真菌药敏试验。所有患者均有眼外伤史。在临床检查中，在三名患者中发现了hypopion。主要的抗真菌药物是外用伏立康唑。治疗后所有患者的视力均在 2-3 周内得到改善。所有四名假性角膜炎患者具有相似的临床特征。准确和快速的物种鉴定应该有助于治疗 p. 博伊迪角膜炎。