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Review article: therapeutic aspects of bile acid signalling in the gut-liver axis
Alimentary Pharmacology & Therapeutics ( IF 6.6 ) Pub Date : 2021-09-23 , DOI: 10.1111/apt.16602
Benedikt Simbrunner 1, 2, 3 , Michael Trauner 1 , Thomas Reiberger 1, 2, 3
Affiliation  

Bile acids are important endocrine modulators of intestinal and hepatic signalling cascades orchestrating critical pathophysiological processes in various liver diseases. Increasing knowledge on bile acid signalling has stimulated the development of synthetic ligands of nuclear bile acid receptors and other bile acid analogues.

中文翻译:

评论文章:胆汁酸信号在肠-肝轴中的治疗方面

胆汁酸是肠道和肝脏信号级联的重要内分泌调节剂,在各种肝脏疾病中协调关键的病理生理过程。对胆汁酸信号传导的认识的增加刺激了核胆汁酸受体和其他胆汁酸类似物的合成配体的发展。
更新日期:2021-10-27
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