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Formation and characterization of microemulsion with novel anionic sodium N-lauroylsarcosinate for personal care
Journal of Molecular Liquids ( IF 5.3 ) Pub Date : 2021-09-24 , DOI: 10.1016/j.molliq.2021.117657
Dhana Lakshmi Manyala 1 , Dharmesh Varade 1
Affiliation  

Microemulsions are unique clear systems comprising of oil, water, surfactant and cosurfactants that offered stimulating perspectives in various applications. The purpose of these study was to create a microemulsion using novel amino acid based anionic sodium N-lauroylsarcosinate (SNLS) surfactant for application in personal care formulations. Triglyceride oils such as caprylic acid, oleic acid and carboxylic acid ester isoamyl acetate were used as oil phase, while short chain alcohols like propanol and butanol were used as cosurfactants. The gradual variations happening in the microstructure of the microemulsions were explored via several complementary characterization techniques. Phase diagrams constructed with or without cosurfactants and using different ratio of surfactant/ cosurfactant (Smix) showed that largest microemulsion region was observed only in the presence of cosurfactant and from Smix of 1:1. Solubility of SNLS in pure water is around 30 wt%, which upsurges in presence of propanol or butanol up to around 85 wt%. This leads to increase in microemulsion region in phase diagram with increasing solubility of oils in the SNLS solution. Microemulsions were relatively stable at an ambient temperature of 27 °C. The optical microscopy, electrical conductivity and viscosity measurement were performed to examine the microstructural changes within the microemulsion region. Three different phases such as water in oil (w/o), bicontinuous, and oil in water (o/w) microemulsion were observed. Foaming behavior specifies increased foam stability of SNLS in the presence of certain amount of oils. Dynamic light scattering study supports the well-defined microemulsion stability even after the manifold dilution. The results obtained from this study may have implications for the developments of an appropriate tactic to prepare stable microemulsion from SNLS which could be exceedingly favorable for personal care formulations.



中文翻译:

用于个人护理的新型阴离子N-月桂酰肌氨酸钠微乳液的形成和表征

微乳液是独特的透明系统,由油、水、表面活性剂和助表面活性剂组成,在各种应用中提供了令人兴奋的前景。这些研究的目的是使用新型氨基酸基阴离子 N-月桂酰肌氨酸钠 (SNLS) 表面活性剂制备微乳液,用于个人护理配方。甘油三酯油如辛酸、油酸和羧酸酯异戊酯用作油相,而短链醇如丙醇和丁醇用作辅助表面活性剂。通过几种互补的表征技术探索了微乳液微观结构中发生的逐渐变化。使用或不使用助表面活性剂以及使用不同比例的表面活性剂/助表面活性剂(S mix)构建的相图) 表明只有在助表面活性剂和S混合物存在时才观察到最大的微乳液区域1:1。SNLS 在纯水中的溶解度约为 30%(重量),在丙醇或丁醇的存在下,溶解度会飙升至 85%(重量)左右。这导致相图中微乳液区域随着油在 SNLS 溶液中溶解度的增加而增加。微乳液在 27 °C 的环境温度下相对稳定。进行光学显微镜、电导率和粘度测量以检查微乳液区域内的微观结构变化。观察到三种不同的相,例如油包水 (w/o)、双连续和水包油 (o/w) 微乳液。起泡行为表明在一定量的油存在下 SNLS 的泡沫稳定性增加。动态光散射研究支持明确定义的微乳液稳定性,即使在多种稀释后也是如此。

更新日期:2021-09-27
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