Members of the REM (Reproductive Meristem) gene family are expressed primarily in reproductive meristems and floral organs. However, their evolution and their functional profiles in flower development remain poorly understood. Here, we performed genome-wide identification and evolutionary analysis of the REM gene family in Rosaceae. This family has been greatly expanded in rose (Rosa chinensis) compared to other species, primarily through tandem duplication. Expression analysis revealed that most RcREM genes are specifically expressed in reproductive organs and that their specific expression patterns are dramatically altered in rose plants with mutations affecting floral organs. Protein-protein interaction analysis indicated that RcREM14 interact with RcAP1 (one of the homology of A class genes in ABCDE model), highlighting the roles of RcREM genes in floral organ identity. Finally, co-expression network analysis indicated that RcREM genes are co-expressed with a high proportion of key genes that regulate flowering time, floral organ development, and cell proliferation and expansion in R. chinensis.

REM（生殖分生组织）基因家族的成员主要在生殖分生组织和花器官中表达。然而，它们的进化及其在花发育中的功能特征仍然知之甚少。在这里，我们对蔷薇科的 REM 基因家族进行了全基因组鉴定和进化分析。与其他物种相比，这个家族在玫瑰（ Rosa chinensis ）中得到了极大的扩展，主要是通过串联复制。表达分析显示，大多数RcREM基因在生殖器官中特异性表达，并且它们的特异性表达模式在玫瑰植物中发生显着改变，突变影响花器官。蛋白质-蛋白质相互作用分析表明RcREM14与RcAP1（ABCDE模型中A类基因的同源性之一）相互作用，突出了RcREM基因在花器官同一性中的作用。最后，共表达网络分析表明，RcREM基因与高比例的调控花时间、花器官发育、细胞增殖和扩张的关键基因共表达。