Volumetric reductions in the hippocampus and the amygdala are considered a hallmark for many psychiatric and neurodegenerative disorders. Because brain atrophy is often observed in disorders that have a higher prevalence in females than males, it has been proposed that sex differences in the aging brain represent a vulnerability factor for developing more severe psychiatric conditions.

中文翻译：

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衰老大脑中的性别差异？海马和杏仁核基于体素的形态测量分析。

海马体和杏仁核的体积减少被认为是许多精神疾病和神经退行性疾病的标志。由于脑萎缩经常出现在女性患病率高于男性的疾病中，因此有人提出，衰老大脑中的性别差异是发展更严重精神疾病的脆弱因素。