Enhanced 13C NMR detects extended reaction networks in living cells,Chemical Communications

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Enhanced 13C NMR detects extended reaction networks in living cells
Chemical Communications ( IF 4.3 ) Pub Date : 2021-09-17 , DOI: 10.1039/d1cc03838a
Pernille Rose Jensen ₁ , Francesca Sannelli ₂ , Ludvig Tving Stauning _{1,

2} , Sebastian Meier ₂

Affiliation

Insights into intracellular chemistry have remained sparse, but would be impactful for the advancement of biomedicine and bioproduction. A suitable ¹³C NMR approach provides improvements in sensitivity that make extended reaction networks and assay time windows, previously inaccessible cell densities and relative flux measurements accessible in living cells.

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