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Postmortem Stability of SARS-CoV-2 in Mouse Lung Tissue
Emerging Infectious Diseases ( IF 7.2 ) Pub Date : 2021-09-23 , DOI: 10.3201/eid2712.211621
Sophie A. Valkenburg , Samuel M.S. Cheng , Asmaa Hachim , Malik Peiris , John Nicholls

The infectivity of severe acute respiratory syndrome coronavirus 2 in deceased persons and organisms remains unclear. We studied transgenic K18 hACE2 mice to determine the kinetics of virus infectivity after host death. Five days after death, virus infectivity in the lung declined by >96% and RNA copies declined by 48.2%.



中文翻译:

SARS-CoV-2 在小鼠肺组织中的死后稳定性

严重急性呼吸系统综合症冠状病毒 2 在死者和生物体中的传染性尚不清楚。我们研究了转基因 K18 hACE2 小鼠,以确定宿主死亡后病毒感染的动力学。死后五天,肺中的病毒感染性下降 > 96%,RNA 拷贝数下降 48.2%。

更新日期:2021-09-24
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