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Limited Protection of Inactivated SARS-CoV-2 Vaccine against Wuhan Strain and Variants of Concern
Emerging Infectious Diseases ( IF 7.2 ) Pub Date : 2021-09-24 , DOI: 10.3201/eid2712.211772 Taweewun Hunsawong , Stefan Fernandez , Rome Buathong , Naretrit Khadthasrima , Kamonthip Rungrojchareonkit , Jindarat Lohachanakul , Rungarun Suthangkornkul , Kedsara Tayong , Angkana T Huang , Chonticha Klungthong , Piyawan Chinnawirotpisan , Yongyuth Poolpanichupatam , Anthony R Jones , Eric D Lombardini , Supaporn Wacharapluesadee , Opass Putcharoen
中文翻译:
灭活 SARS-CoV-2 疫苗对武汉毒株和关注变种的保护有限
更新日期:2021-09-24
Emerging Infectious Diseases ( IF 7.2 ) Pub Date : 2021-09-24 , DOI: 10.3201/eid2712.211772 Taweewun Hunsawong , Stefan Fernandez , Rome Buathong , Naretrit Khadthasrima , Kamonthip Rungrojchareonkit , Jindarat Lohachanakul , Rungarun Suthangkornkul , Kedsara Tayong , Angkana T Huang , Chonticha Klungthong , Piyawan Chinnawirotpisan , Yongyuth Poolpanichupatam , Anthony R Jones , Eric D Lombardini , Supaporn Wacharapluesadee , Opass Putcharoen
In vitro determination of severe acute respiratory syndrome coronavirus 2 neutralizing antibodies induced in serum samples from recipients of the CoronaVac vaccine showed a short protection period against the original virus strain and limited protection against variants of concern. These data provide support for vaccine boosters, especially variants of concern circulate.
中文翻译:
灭活 SARS-CoV-2 疫苗对武汉毒株和关注变种的保护有限
CoronaVac 疫苗接受者的血清样本中诱导的严重急性呼吸系统综合症冠状病毒 2 中和抗体的体外测定表明,对原始病毒株的保护期很短,对相关变异的保护作用有限。这些数据为疫苗加强剂提供了支持,尤其是关注的变种传播。