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Evaluation of medullary cytokine expression and clinical and laboratory aspects in severe human visceral leishmaniasis
Parasite Immunology ( IF 1.4 ) Pub Date : 2021-09-24 , DOI: 10.1111/pim.12880
Leandro de Freitas Teles 1 , Agostinho Gonçalves Viana 2 , Mariana Santos Cardoso 2 , Guilherme Rafael Gomide Pinheiro 3 , Gabriele Ariadine Bento 2 , Jamille Fernandes Lula 1 , Tânia de Cássia Moreira Soares 1 , Ricardo Toshio Fujiwara 2 , Silvio Fernando Guimarães de Carvalho 1
Affiliation  

Visceral leishmaniasis (VL) is a serious public health problem. The factors that can determine whether VL develops and progresses to severe form have not been fully identified, but a specific cellular immune response appears to play a key role. Therefore, understanding immunopathogenesis can be useful in preventing a serious clinical outcome.

中文翻译:

严重人内脏利什曼病的髓质细胞因子表达及临床和实验室方面的评估

内脏利什曼病 (VL) 是一个严重的公共卫生问题。可以确定 VL 是否发展并进展为严重形式的因素尚未完全确定,但特定的细胞免疫反应似乎起着关键作用。因此,了解免疫发病机制有助于预防严重的临床结果。
更新日期:2021-11-12
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